Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RB1 | P06400 | 7/20 | 0.52 |
| ▸ | CDC42 | P60953 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | BRD3 | Q15059 | 4/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4192405 | 0.88 | RB1 (0.60) | RB1CDC42GAACASP6BRD3 | |
| Hydrochloric Acid SCHEMBL4157308 | 0.87 | RB1 (0.60) | RB1CDC42GAACASP6BRD3 | |
| SCHEMBL31497427 | 0.86 | RB1 (0.55) | RB1CDC42GAACASP6BRD3 | |
| SCHEMBL31497396 | 0.86 | CDC42 (0.57) | RB1CDC42GAACASP6BRD3 | |
| SCHEMBL31497401 | 0.83 | RB1 (0.52) | RB1CDC42GAACASP6BRD3 | |
| SCHEMBL31497468 | 0.83 | RB1 (0.52) | RB1CDC42GAACASP6BRD3 | |
| SCHEMBL31497362 | 0.82 | CDC42 (0.53) | RB1CDC42GAACASP6BRD3 | |
| SCHEMBL31497389 | 0.81 | SIRT1 (0.53) | RB1CDC42GAACASP6BRD3 | |
| SCHEMBL28489487 | 0.80 | PRMT5 (0.59) | RB1CDC42GAACASP6BRD3 | |
| SCHEMBL15450584 | 0.79 | RB1 (0.57) | RB1CDC42BRD3SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119490487-A | Polysubstituted tetrahydrocarbazole compound, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2025-02-21 | — | — | CN | disclosed |