SCHEMBL31498142

SCHEMBL31498142

Cc1[nH]c2cc(OCc3ccccc3)ccc2c1C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 7/20 0.61
CTSV O60911 3/20 0.60
CTSL P07711 3/20 0.60
TRPM8 Q7Z2W7 1/20 0.57
MAOB P27338 5/20 0.52
ACHE P22303 1/20 0.52
IMPDH2 P12268 1/20 0.51
GABRA1 P14867 1/20 0.50
GABRG2 P18507 1/20 0.50
GABRB3 P28472 1/20 0.50
GABRA3 P34903 1/20 0.50
GABRA2 P47869 1/20 0.50
ALOX5 P09917 1/20 0.49
ALDH1A1 P00352 1/20 0.48
HPGD P15428 1/20 0.48
MDH2 P40926 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
NPC1 O15118 1/20 0.48
CASP3 P42574 1/20 0.48
RAB9A P51151 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13399696 0.83 CTSV (0.59) MAOACTSVCTSLTRPM8MAOB
SCHEMBL27590189 0.83 MAOA (0.56) MAOACTSVCTSLTRPM8MAOB
SCHEMBL7255064 0.82 MAOA (0.64) MAOACTSVCTSLTRPM8MAOB
SCHEMBL9689455 0.81 MAOA (0.54) MAOACTSVCTSLTRPM8MAOB
SCHEMBL31498177 0.81 PARP15 (0.55) MAOACTSVCTSLTRPM8MAOB
SCHEMBL7253632 0.81 CTSV (0.66) MAOACTSVCTSLTRPM8MAOB
SCHEMBL7256169 0.81 CTSV (0.66) MAOACTSVCTSLMAOBIMPDH2
SCHEMBL5193310 0.80 PPARG (0.56) MAOAMAOBACHE
SCHEMBL14422827 0.80 CTSV (0.83) MAOACTSVCTSLTRPM8MAOB
SCHEMBL2795363 0.80 CTSV (0.65) MAOACTSVCTSLMAOBACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119677717-A Indolazine derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-03-21 CN disclosed