SCHEMBL31498181

SCHEMBL31498181

Cc1cc2ccc(OCC3CC3)cc2[nH]1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 6/20 0.49
SLC6A4 P31645 6/20 0.49
HTR3A P46098 2/20 0.49
KCNH2 Q12809 2/20 0.49
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
SLC6A3 Q01959 3/20 0.46
PARP15 Q460N3 4/20 0.46
PARP10 Q53GL7 4/20 0.46
AXL P30530 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40
GRIN2C Q14957 1/20 0.40
GRIN3A Q8TCU5 1/20 0.40
BRD4 O60885 1/20 0.40
CREBBP Q92793 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3623576 0.79 SLC6A2 (0.47) SLC6A2SLC6A4HTR3AKCNH2MAOA
SCHEMBL3626472 0.79 SLC6A2 (0.47) SLC6A2SLC6A4HTR3AKCNH2MAOA
SCHEMBL3618002 0.78 PARP15 (0.46) SLC6A2SLC6A4HTR3AKCNH2MAOA
SCHEMBL3623549 0.77 XDH (0.53) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL14364984 0.77 GRIN2D (0.44) SLC6A2SLC6A4HTR3AKCNH2SLC6A3
SCHEMBL11612222 0.76 CA12 (0.45) MAOAMAOBAXL
SCHEMBL30048882 0.76 MEN1 (0.54) SLC6A2SLC6A4HTR3AKCNH2MAOA
SCHEMBL19510727 0.76 MEN1 (0.54) SLC6A2SLC6A4HTR3AKCNH2MAOA
SCHEMBL28962410 0.75 MAOA (0.50) MAOAAXLTDP1
SCHEMBL31498193 0.75 MAOB (0.54) SLC6A2SLC6A4HTR3AKCNH2MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119677717-A Indolazine derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-03-21 CN disclosed