SCHEMBL3149867 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	MAPK14	Q16539	16/20	0.38

▸	MAPK11	Q15759	4/20	0.38

▸	MAPK13	O15264	1/20	0.35

▸	MAPK12	P53778	1/20	0.35

▸	HTR5A	P47898	1/20	0.33

▸	KIT	P10721	1/20	0.33

▸	SIGMAR1	Q99720	1/20	0.33

▸	PI4KA	P42356	1/20	0.32

▸	PI4K2B	Q8TCG2	1/20	0.32

▸	PI4K2A	Q9BTU6	1/20	0.32

▸	PI4KB	Q9UBF8	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3154098	0.89	HTR7 (0.34)	MAPK14MAPK11PI4KAPI4K2BPI4K2A
SCHEMBL3148991	0.75	MAPK14 (0.49)	MAPK14KIT
SCHEMBL3154106	0.73	MAPK14 (0.49)	MAPK14MAPK11
SCHEMBL3146065	0.72	MAPK14 (0.48)	MAPK14MAPK11MAPK13MAPK12KIT
SCHEMBL3149695	0.72	MAPK14 (0.41)	MAPK14
SCHEMBL3149778	0.71	MAPK14 (0.48)	MAPK14
SCHEMBL3145569	0.70	MAPK14 (0.50)	MAPK14KIT
SCHEMBL3145748	0.69	MAPK14 (0.48)	MAPK14MAPK11
SCHEMBL3148658	0.69	MAPK14 (0.48)	MAPK14KIT
SCHEMBL3144145	0.68	MAPK14 (0.53)	MAPK14MAPK11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1699800-B1	BICYCLIC HETEROCYCLIC P-38 KINASE INHIBITORS	NOVARTIS AG (CH)	2010-02-10	—	—	EP	claimed