Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | ADK | P55263 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31499339 | 0.81 | MEN1 (0.45) | ESR1ESR2SCN9ABCHEKDM1A | |
| SCHEMBL17583721 | 0.79 | ESR1 (0.39) | ESR1ESR2SCN9ABCHESTING1 | |
| SCHEMBL17583578 | 0.78 | SCN9A (0.44) | ESR1ESR2SCN9AGSK3BADK | |
| SCHEMBL31499361 | 0.75 | BCHE (0.31) | BCHE | |
| SCHEMBL22416385 | 0.68 | SCN9A (0.37) | SCN9AGSK3BADKKDM4EACHE | |
| SCHEMBL28698842 | 0.67 | CDC25A (0.41) | KDM4EEGFR | |
| SCHEMBL28357769 | 0.66 | AADAT (0.36) | KDM4EEGFR | |
| SCHEMBL31499333 | 0.64 | BCHE (0.44) | BCHESTING1GSK3BACHEKDM1A | |
| SCHEMBL18025750 | 0.64 | PDE4A (0.51) | GSK3BKDM4ESLC6A2MMP13SLC6A3 | |
| SCHEMBL13617411 | 0.63 | MAPT (0.57) | GSK3BKDM4EHTR2BCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954707-A | Chiral 3, 3-disubstituted indolone compound and preparation method and application thereof | 云南大学 | 2025-05-09 | — | — | CN | disclosed |