Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31499328 | 1.00 | LMNA (0.49) | LMNAMAPTCYP1A2CYP2A6KMT2A | |
| SCHEMBL31499330 | 0.83 | LMNA (0.73) | LMNAMAPTKMT2AMEN1XBP1 | |
| SCHEMBL31499369 | 0.82 | LMNA (0.51) | LMNAMAPTCYP1A2CYP2A6KMT2A | |
| SCHEMBL31499327 | 0.82 | LMNA (0.51) | LMNAMAPTCYP1A2CYP2A6KMT2A | |
| SCHEMBL5478595 | 0.80 | CHRM2 (0.57) | LMNAMAPTKMT2AMEN1XBP1 | |
| SCHEMBL11751065 | 0.80 | MAPT (0.46) | LMNAMAPTKMT2AMEN1XBP1 | |
| SCHEMBL31499349 | 0.79 | LMNA (0.71) | LMNAMAPTKMT2AMEN1XBP1 | |
| SCHEMBL31499321 | 0.79 | LMNA (0.71) | LMNAMAPTKMT2AMEN1XBP1 | |
| SCHEMBL17813120 | 0.77 | MAPT (0.69) | LMNAMAPTKMT2AMEN1XBP1 | |
| SCHEMBL11751056 | 0.76 | MAPT (0.45) | LMNAMAPTKMT2AMEN1XBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954707-A | Chiral 3, 3-disubstituted indolone compound and preparation method and application thereof | 云南大学 | 2025-05-09 | — | — | CN | disclosed |