Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | SI | P14410 | 4/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31499349 | 1.00 | LMNA (0.71) | LMNACHRM2ADORA3KCNH2MAPT | |
| SCHEMBL31499330 | 0.95 | LMNA (0.73) | LMNACHRM2ADORA3KCNH2MAPT | |
| SCHEMBL2715686 | 0.84 | LMNA (1.00) | LMNACHRM2ADORA3KCNH2MAPT | |
| SCHEMBL31499327 | 0.81 | LMNA (0.51) | LMNACHRM2ADORA3KCNH2MAPT | |
| SCHEMBL31499369 | 0.81 | LMNA (0.51) | LMNACHRM2ADORA3KCNH2MAPT | |
| SCHEMBL31499345 | 0.79 | LMNA (0.49) | LMNACHRM2ADORA3KCNH2MAPT | |
| SCHEMBL31499328 | 0.79 | LMNA (0.49) | LMNACHRM2ADORA3KCNH2MAPT | |
| SCHEMBL2716060 | 0.78 | CHRM2 (0.93) | LMNACHRM2ADORA3KCNH2MAPT | |
| SCHEMBL22632192 | 0.78 | LMNA (0.80) | LMNACHRM2ADORA3KCNH2MAPT | |
| SCHEMBL25311834 | 0.77 | MAPT (0.43) | LMNACHRM2ADORA3KCNH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954707-A | Chiral 3, 3-disubstituted indolone compound and preparation method and application thereof | 云南大学 | 2025-05-09 | — | — | CN | disclosed |