Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 8/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.53 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.53 |
| ▸ | JUN | P05412 | 2/20 | 0.53 |
| ▸ | IGF1R | P08069 | 13/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | INSR | P06213 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22228848 | 0.90 | CDK2 (0.53) | CDK2MAPK8MAPK9JUNIGF1R | |
| SCHEMBL22252970 | 0.90 | IGF1R (0.48) | CDK2MAPK8MAPK9JUNIGF1R | |
| SCHEMBL20460640 | 0.87 | MAPK10 (0.58) | CDK2MAPK8MAPK9JUNIGF1R | |
| SCHEMBL22228927 | 0.83 | CDK2 (0.51) | CDK2MAPK8MAPK9JUNIGF1R | |
| SCHEMBL22228925 | 0.83 | CDK2 (0.51) | CDK2MAPK8MAPK9JUNIGF1R | |
| SCHEMBL31501022 | 0.81 | CDK9 (0.58) | CDK2MAPK8MAPK9JUNIGF1R | |
| SCHEMBL31501018 | 0.81 | CDK9 (0.58) | CDK2MAPK8MAPK9JUNIGF1R | |
| SCHEMBL22228715 | 0.81 | CDK9 (0.58) | CDK2MAPK8MAPK9JUNIGF1R | |
| SCHEMBL31501021 | 0.81 | CDK9 (0.58) | CDK2MAPK8MAPK9JUNIGF1R | |
| SCHEMBL22228694 | 0.81 | CDK2 (0.62) | CDK2MAPK8MAPK9JUNIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3577116-B1 | DERIVATIVES OF N-CYCLOALKYL/HETEROCYCLOALKYL-4-(IMIDAZO[1,2-A]PYRIDINE)PYRIMIDIN-2-AMINE AS THERAPEUTIC AGENTS | CHANGZHOU QIANHONG BIO PHARMA CO LTD (CN) | 2025-04-23 | — | — | EP | disclosed |