Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3675046 | 0.82 | ESR1 (0.41) | ESR1ESR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL3150471 | 0.81 | ESR1 (0.35) | ESR1ESR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL3146501 | 0.80 | MAPT (0.50) | PDE4DKDM4EMEN1LMNAMAPT | |
| SCHEMBL2710475 | 0.79 | ESR1 (0.38) | ESR1ESR2ALDH1A1TDP1PDE4D | |
| SCHEMBL10299748 | 0.79 | ALK (0.36) | ESR1ESR2PDE4D | |
| SCHEMBL3155226 | 0.78 | ESR1 (0.41) | ESR1ESR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL30362289 | 0.77 | CYP3A4 (0.50) | ESR1ESR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL2810033 | 0.77 | CYP3A4 (0.50) | ESR1ESR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL29684394 | 0.75 | PDK2 (0.33) | PDE4D | |
| SCHEMBL449262 | 0.75 | PDK2 (0.33) | PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8218937-B2 | Optical film, image display device, diethynylfluorene, and polymer thereof | NITTO DENKO CORPORATION (JP) | 2012-07-10 | — | — | US | disclosed |
| US-20100003490-A1 | OPTICAL FILM, IMAGE DISPLAY DEVICE, DIETHYNYLFLUORENE, AND POLYMER THEREOF | NITTO DENKO CORPORATION (JP) | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100003490-A1 | OPTICAL FILM, IMAGE DISPLAY DEVICE, DIETHYNYLFLUORENE, AND POLYMER THEREOF | PDCD2L, FMNL1, MACF1 | ESR1 4587/4885ESR2 4527/4885ALDH1A1 2272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.