Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 7/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.57 |
| ▸ | MAPK6 | Q16659 | 5/20 | 0.57 |
| ▸ | MAPKAPK3 | Q16644 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | ITK | Q08881 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1145076 | 1.00 | MAP2K4 (0.57) | MAP2K4MAPK1MAPK6MAPKAPK3KDM4E | |
| SCHEMBL16308650 | 0.86 | KIF11 (0.50) | MAP2K4MAPK1MAPK6MAPKAPK3KDM4E | |
| SCHEMBL1144879 | 0.86 | DYRK1A (0.52) | MAP2K4MAPK1MAPK6MAPKAPK3KDM4E | |
| SCHEMBL31746650 | 0.86 | DYRK1A (0.52) | MAP2K4MAPK1MAPK6MAPKAPK3KDM4E | |
| SCHEMBL23559721 | 0.85 | MAP2K4 (0.58) | MAP2K4MAPK1MAPK6MAPKAPK3MAPKAPK2 | |
| SCHEMBL21509969 | 0.84 | MAP2K4 (0.60) | MAP2K4MAPK1MAPK6MAPKAPK3LMNA | |
| SCHEMBL6618549 | 0.82 | ADORA2A (0.43) | MAP2K4MAPK1MAPK6MAPKAPK3MAPKAPK2 | |
| SCHEMBL14872686 | 0.82 | MAPK1 (0.65) | MAP2K4MAPK1MAPK6MAPKAPK3MAPK3 | |
| SCHEMBL1501529 | 0.82 | KDM4E (0.55) | MAP2K4KDM4EALDH1A1HPGDDYRK1A | |
| SCHEMBL4403122 | 0.82 | MAPK1 (0.43) | MAP2K4MAPK1MAPK6MAPKAPK3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427035-B | ENL/AF9 YEATS inhibitors | 洛克菲勒大学 | 2025-04-22 | — | — | CN | disclosed |