Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 2/20 | 0.37 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.37 |
| ▸ | CDK9 | P50750 | 5/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | CCNK | O75909 | 1/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 2/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.34 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.34 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29072084 | 0.86 | SMARCA2 (0.49) | SMARCA2SMARCA4PBRM1KITCCNK | |
| SCHEMBL29619449 | 0.86 | SMARCA2 (0.49) | SMARCA2SMARCA4PBRM1KITCCNK | |
| SCHEMBL31505531 | 0.83 | CCNT1 (0.41) | SMARCA2SMARCA4PBRM1CCNT1CDK9 | |
| SCHEMBL31505585 | 0.81 | HDAC2 (0.38) | SMARCA2SMARCA4PBRM1KITMERTK | |
| SCHEMBL30658000 | 0.79 | SMARCA2 (0.38) | SMARCA2SMARCA4PBRM1CCNT1CDK9 | |
| SCHEMBL26654056 | 0.79 | SMARCA2 (0.38) | SMARCA2SMARCA4PBRM1CCNT1CDK9 | |
| SCHEMBL30682962 | 0.78 | SMARCA2 (0.39) | SMARCA2SMARCA4PBRM1KITJAK2 | |
| SCHEMBL31505631 | 0.77 | KCNK3 (0.31) | SMARCA2SMARCA4PBRM1MERTK | |
| SCHEMBL31505550 | 0.76 | KLKB1 (0.33) | SMARCA2SMARCA4PBRM1CCNT1CDK9 | |
| SCHEMBL31505633 | 0.76 | TACR1 (0.39) | SMARCA2SMARCA4PBRM1CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025101944-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT DEGRADE SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A | Plexium, Inc. (US) | 2025-05-15 | — | — | WO | disclosed |