Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 3/20 | 0.49 |
| ▸ | SMARCA4 | P51532 | 3/20 | 0.49 |
| ▸ | PBRM1 | Q86U86 | 3/20 | 0.49 |
| ▸ | CCNK | O75909 | 1/20 | 0.37 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 3/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29619449 | 1.00 | SMARCA2 (0.49) | SMARCA2SMARCA4PBRM1CCNKCDK12 | |
| SCHEMBL29619378 | 0.86 | PBRM1 (0.44) | SMARCA2SMARCA4PBRM1 | |
| SCHEMBL31505584 | 0.86 | SMARCA2 (0.37) | SMARCA2SMARCA4PBRM1CCNKCDK12 | |
| SCHEMBL27040439 | 0.82 | PBRM1 (0.36) | SMARCA2SMARCA4PBRM1 | |
| SCHEMBL24461526 | 0.81 | SMARCA2 (0.53) | SMARCA2SMARCA4PBRM1CCNKCDK12 | |
| SCHEMBL29619399 | 0.81 | SMARCA2 (0.53) | SMARCA2SMARCA4PBRM1CCNKCDK12 | |
| SCHEMBL29619413 | 0.80 | SMARCA2 (0.52) | SMARCA2SMARCA4PBRM1CCNKCDK12 | |
| SCHEMBL24461312 | 0.80 | SMARCA2 (0.52) | SMARCA2SMARCA4PBRM1CCNKCDK12 | |
| SCHEMBL27053152 | 0.80 | PBRM1 (0.38) | SMARCA2SMARCA4PBRM1 | |
| SCHEMBL24461256 | 0.78 | PBRM1 (0.39) | SMARCA2SMARCA4PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116744929-A | Compounds and uses thereof | 福霍恩治疗公司 | 2023-09-12 | — | — | CN | disclosed |