Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3151386 | 0.90 | CYP11B1 (0.36) | CYP11B1CYP11B2CYP46A1CYP4F2CYP4A11 | |
| SCHEMBL3151304 | 0.90 | CYP11B1 (0.39) | CYP11B1CYP11B2AKR1C3AKR1C2 | |
| SCHEMBL3137211 | 0.88 | FFAR4 (0.38) | FFAR4 | |
| SCHEMBL3155887 | 0.88 | FFAR4 (0.36) | FFAR4 | |
| SCHEMBL3147054 | 0.87 | FFAR4 (0.38) | CYP11B1CYP11B2FFAR4 | |
| SCHEMBL3138316 | 0.87 | KDM1A (0.41) | — | |
| SCHEMBL3779567 | 0.85 | FFAR4 (0.32) | CYP11B1CYP11B2CYP4F2CYP4A11FFAR4 | |
| SCHEMBL3151485 | 0.84 | SLC6A9 (0.37) | — | |
| SCHEMBL3151351 | 0.82 | PTGDR2 (0.38) | — | |
| SCHEMBL3145775 | 0.80 | CYP11B1 (0.40) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979321-B9 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2010-02-17 | — | — | EP | disclosed |
| EP-1979321-B1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2009-07-29 | — | — | EP | disclosed |