Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 18/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.37 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3141821 | 0.92 | KDM1A (0.41) | KDM1AMAOBAKT1KCNH2RCOR1 | |
| SCHEMBL3151351 | 0.89 | PTGDR2 (0.38) | — | |
| SCHEMBL3155887 | 0.88 | FFAR4 (0.36) | — | |
| SCHEMBL3137211 | 0.88 | FFAR4 (0.38) | MAP4K4 | |
| SCHEMBL3150873 | 0.87 | CYP11B1 (0.35) | — | |
| SCHEMBL3146059 | 0.84 | XDH (0.43) | KDM1AAKT1KCNH2CHRNB2CHRNA4 | |
| SCHEMBL3151304 | 0.83 | CYP11B1 (0.39) | — | |
| SCHEMBL3260962 | 0.82 | PTGDR2 (0.38) | KDM1A | |
| SCHEMBL3151485 | 0.81 | SLC6A9 (0.37) | CHRNB2CHRNA4MAP4K4 | |
| SCHEMBL3779591 | 0.80 | EGLN1 (0.38) | KDM1AMAOBAKT1KCNH2RCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979321-B9 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2010-02-17 | — | — | EP | disclosed |
| EP-1979321-B1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2009-07-29 | — | — | EP | disclosed |