Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B known ✓ | P49841 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | PKLR | P30613 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL890883 | 0.92 | TSHR (0.47) | TSHRSMN1; SMN2HDAC6TDP1KMT2A | |
| SCHEMBL31367286 | 0.92 | TSHR (0.47) | TSHRSMN1; SMN2HDAC6TDP1KMT2A | |
| Lithium Ion SCHEMBL29733519 | 0.92 | PTGS2 (0.39) | TDP1KMT2APTPN1DUSP5POLB | |
| SCHEMBL2638757 | 0.91 | TSHR (0.45) | TSHRSMN1; SMN2HDAC6TDP1KMT2A | |
| SCHEMBL10966987 | 0.91 | TSHR (0.48) | TSHRSMN1; SMN2HDAC6TDP1KMT2A | |
| SCHEMBL9568749 | 0.91 | TSHR (0.48) | TSHRSMN1; SMN2HDAC6TDP1KMT2A | |
| SCHEMBL28692298 | 0.89 | TSHR (0.47) | TSHRSMN1; SMN2HDAC6TDP1KMT2A | |
| SCHEMBL9568744 | 0.89 | TSHR (0.47) | TSHRSMN1; SMN2HDAC6TDP1KMT2A | |
| SCHEMBL2638755 | 0.89 | LMNA (0.40) | TDP1KMT2APTPN1DUSP5PKLR | |
| SCHEMBL30507562 | 0.89 | LMNA (0.40) | TDP1KMT2APTPN1DUSP5PKLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025037701-A1 | SOLID SECONDARY BATTERY AND MANUFACTURING METHOD THEREFOR | 삼성에스디아이주식회사 | 2025-02-20 | — | — | WO | disclosed |