Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | AGPAT2 | O15120 | 4/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2252229 | 1.00 | MCHR1 (0.48) | MCHR1ALDH1A1KDM4ENCF1MAPK1 | |
| SCHEMBL5431429 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPK1HSP90AA1HSP90AB1 | |
| SCHEMBL9810196 | 0.77 | MCHR1 (0.52) | MCHR1ALDH1A1KDM4ENCF1MAPK1 | |
| SCHEMBL28064741 | 0.76 | HSP90AA1 (0.51) | MCHR1ALDH1A1KDM4EHSP90AA1HSP90AB1 | |
| SCHEMBL7226169 | 0.76 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPK1HSP90AA1HSP90AB1 | |
| SCHEMBL3771034 | 0.76 | NOS3 (0.54) | MCHR1ALDH1A1KDM4ENCF1MAPK1 | |
| SCHEMBL359862 | 0.76 | MCHR1 (0.50) | MCHR1ALDH1A1KDM4ENCF1MAPK1 | |
| SCHEMBL7970266 | 0.76 | MCHR1 (0.50) | MCHR1ALDH1A1KDM4ENCF1MAPK1 | |
| SCHEMBL7849602 | 0.74 | TLR8 (0.44) | MCHR1ALDH1A1KDM4EMAPK1HSP90AA1 | |
| SCHEMBL5696517 | 0.74 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPK1HSP90AA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025081019-A1 | KIF MODULATOR COMPOUNDS AND METHODS OF USE | IAMBIC THERAPEUTICS, INC. (US) | 2025-04-17 | — | — | WO | disclosed |