Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.46 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | NOS2 | P35228 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31512068 | 0.77 | ALOX5AP (0.43) | KEAP1MAPK10PIK3CBADORA2ALRRK2 | |
| SCHEMBL31415329 | 0.76 | KEAP1 (0.55) | KEAP1PIK3CBKMT2APIK3CDPIK3CG | |
| SCHEMBL19480882 | 0.73 | CYP2A6 (0.46) | NOS3NOS1NOS2KEAP1MAPK10 | |
| SCHEMBL28365466 | 0.70 | KEAP1 (0.61) | NOS3NOS2KEAP1PIK3CBADORA2A | |
| SCHEMBL30269965 | 0.70 | KEAP1 (0.61) | NOS3NOS2KEAP1PIK3CBADORA2A | |
| SCHEMBL25742607 | 0.70 | KEAP1 (0.47) | KEAP1MAPK10PIK3CBADORA2AKMT2A | |
| SCHEMBL23107322 | 0.69 | KMT2A (0.35) | KEAP1MAPK10KMT2AJMJD6 | |
| Hydrochloric Acid SCHEMBL31512090 | 0.69 | GRM4 (0.38) | NOS3NOS1NOS2PIK3CBJAK2 | |
| SCHEMBL16911518 | 0.69 | KDM4E (0.47) | KEAP1KMT2ACYP3A4S1PR2JMJD6 | |
| SCHEMBL20912065 | 0.69 | KMT2A (0.40) | KEAP1MAPK10KMT2AS1PR2JMJD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054366-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | NICO THERAPEUTICS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |