Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 9/20 | 0.39 |
| ▸ | ACHE | P22303 | 9/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.36 |
| ▸ | WNT3A | P56704 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20590974 | 0.90 | COMT (0.57) | COMTBCHEACHECHRM2CHRM1 | |
| SCHEMBL29642857 | 0.90 | COMT (0.57) | COMTBCHEACHECHRM2CHRM1 | |
| SCHEMBL31514940 | 0.85 | COMT (0.50) | COMTBCHEACHECYP1A2HSP90AA1 | |
| SCHEMBL31514939 | 0.85 | COMT (0.50) | COMTBCHEACHECYP1A2HSP90AA1 | |
| SCHEMBL31514937 | 0.84 | COMT (0.49) | COMTBCHEACHECYP1A2HSP90AA1 | |
| SCHEMBL19014910 | 0.80 | ACHE (0.42) | COMTBCHEACHECHRM2CHRM1 | |
| SCHEMBL31514933 | 0.79 | COMT (0.42) | COMTBCHEACHEHSP90AA1HSP90AB1 | |
| SCHEMBL31514944 | 0.79 | COMT (0.42) | COMTBCHEACHEHSP90AA1HSP90AB1 | |
| SCHEMBL31514938 | 0.76 | COMT (0.55) | COMTCYP1A2HSP90AA1HSP90AB1BLM | |
| SCHEMBL19014907 | 0.75 | ACHE (0.40) | COMTBCHEACHECHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390351-B1 | NOVEL BICYCLIC-COMPOUNDS FOR USE AS A MEDICAMENT, IN PARTICULAR FOR TREATMENT OF PARKINSON'S DISEASE | KOESTER HUBERT (DE) | 2025-02-26 | — | — | EP | claimed |
| EP-3390351-B1 | NOVEL BICYCLIC-COMPOUNDS FOR USE AS A MEDICAMENT, IN PARTICULAR FOR TREATMENT OF PARKINSON'S DISEASE | KOESTER HUBERT (DE) | 2025-02-26 | — | — | EP | disclosed |