Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.33 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL173999 | 0.88 | KDM4E (0.41) | SMN1; SMN2KDM4EMAPTTHRBGAA | |
| SCHEMBL6783179 | 0.85 | KDM4E (0.40) | SMN1; SMN2KDM4EMAPTTHRBELANE | |
| SCHEMBL6621580 | 0.85 | NPC1 (0.42) | SMN1; SMN2KDM4EMAPTTHRBELANE | |
| SCHEMBL10255933 | 0.84 | KDM4E (0.41) | USP2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL31517346 | 0.82 | KDM4E (0.35) | KDM4EMAPTTHRBELANEHTT | |
| SCHEMBL31517302 | 0.79 | KCNJ6 (0.35) | KDM4EMAPTTHRBELANENR1H2 | |
| SCHEMBL174902 | 0.77 | ALDH1A1 (0.43) | KDM4EELANENR1H2HSP90AA1HSP90AB1 | |
| SCHEMBL25249092 | 0.73 | HSP90AA1 (0.43) | SMN1; SMN2KDM4EMAPTTHRBELANE | |
| SCHEMBL667656 | 0.73 | KDM4E (0.40) | KDM4EMAPTTHRBELANENR1H2 | |
| SCHEMBL23500483 | 0.73 | FAAH (0.38) | KDM4EMAPTTHRBELANENR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025040546-A1 | PYRAZOLE COMPOUNDS AS CULLIN RING UBIQUITIN LIGASE COMPOUNDS | PROXYGEN GMBH (AT) | 2025-02-27 | — | — | WO | disclosed |