Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | AKT2 | P31751 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26601781 | 1.00 | AKT1 (0.38) | AKT1AKT2PLAUSTAT3HTT | |
| SCHEMBL26708517 | 0.76 | ALOX5AP (0.34) | STAT3HTTSMN1; SMN2PTGER1PDE4B | |
| SCHEMBL31747909 | 0.76 | ALOX5AP (0.34) | STAT3HTTSMN1; SMN2PTGER1PDE4B | |
| SCHEMBL26708700 | 0.74 | ALOX5AP (0.36) | STAT3HTTSMN1; SMN2GCK | |
| SCHEMBL9878241 | 0.72 | TSHR (0.38) | SMN1; SMN2PDE4BPDE4D | |
| SCHEMBL31517839 | 0.71 | PDK1 (0.39) | AKT1AKT2STAT3HTTSMN1; SMN2 | |
| SCHEMBL26601795 | 0.70 | TNKS (0.34) | SMN1; SMN2PDE4BPDE4D | |
| SCHEMBL31517844 | 0.68 | CHRNA7 (0.51) | GAASLC6A4 | |
| SCHEMBL26607243 | 0.68 | SMN1; SMN2 (0.51) | STAT3HTTSMN1; SMN2 | |
| SCHEMBL9878787 | 0.68 | PDE4B (0.38) | HTTSMN1; SMN2PDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090480-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-05-01 | — | — | WO | disclosed |