Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | LSS | P48449 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL15391253 | 0.92 | DRD2 (0.55) | HTR3ADRD2SLC2A1SLC18A3LMNA | |
| SCHEMBL18533598 | 0.92 | HTR3A (0.52) | HTR3ADRD2SLC2A1SLC18A3LMNA | |
| SCHEMBL23578560 | 0.90 | HTR3A (0.50) | HTR3ADRD2SLC2A1SLC18A3LMNA | |
| SCHEMBL19950989 | 0.90 | MEN1 (0.59) | HTR3ADRD2SLC2A1SLC18A3LMNA | |
| SCHEMBL218475 | 0.89 | HTR3A (0.59) | HTR3ADRD2SLC2A1SLC18A3LMNA | |
| SCHEMBL435619 | 0.89 | HTR3A (0.59) | HTR3ADRD2SLC2A1SLC18A3LMNA | |
| Bicarbonate SCHEMBL1719769 | 0.88 | IDO1 (0.51) | HTR3ADRD2SLC2A1SLC18A3LMNA | |
| SCHEMBL8594378 | 0.88 | HTR3A (0.48) | HTR3ADRD2SLC2A1SLC18A3LMNA | |
| SCHEMBL8594377 | 0.88 | HTR3A (0.48) | HTR3ADRD2SLC2A1SLC18A3LMNA | |
| SCHEMBL1570625 | 0.88 | KDM1A (0.49) | HTR3ADRD2SLC2A1SLC18A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115572098-A | Concrete additive and preparation method thereof | 光明铁道控股有限公司 | 2023-01-06 | — | — | CN | claimed |
| EP-3089980-B1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2018-01-31 | — | — | EP | claimed |
| EP-2794573-B1 | NOVEL INSECTICIDAL AROMATIC AMIDES | BAYER IP GMBH (DE) | 2017-08-30 | — | — | EP | claimed |
| US-9670208-B2 | Serine/threonine kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2017-06-06 | — | — | US | claimed |
| US-9573966-B2 | Anti-cancer activity of novel bicyclic heterocycles | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U.LEUVEN R&D (BE) | 2017-02-21 | — | — | US | claimed |
| EP-3089980-A1 | SERINE/THREONINE KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2016-11-09 | — | — | EP | claimed |
| US-20160304519-A1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2016-10-20 | — | — | US | claimed |
| EP-2616077-B1 | ANTI-CANCER ACTIVITY OF NOVEL BICYCLIC HETEROCYCLES | UNIV LEUVEN KATH (BE) | 2016-08-31 | — | — | EP | claimed |
| EP-2782903-B1 | NOVEL PYRROLIDINE DERIVATIVES AS INHIBITORS OF CATHEPSIN | HOFFMANN LA ROCHE (CH) | 2016-04-06 | — | — | EP | claimed |
| US-9204645-B2 | Insecticidal aromatic amides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-08 | — | — | US | claimed |
| US-20090023740-A1 | SODIUM CHANNEL INHIBITORS | ICAGEN (US) | 2009-01-22 | — | — | US | claimed |
| WO-2009012242-A2 | SODIUM CHANNEL INHIBITORS | ICAGEN, INC. (US) | 2009-01-22 | — | — | WO | claimed |
| EP-1756063-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-02-28 | — | — | EP | claimed |
| WO-2005110992-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2005-11-24 | — | — | WO | claimed |
| US-5051447-A | Applying aromatic oximes to plants, seeds or soils | BASF AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | claimed |
| EP-0179788-B1 | PESTICIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1991-06-12 | — | — | EP | claimed |
| EP-0354571-A1 | Oximethers, method for their preparation and fungicides containing them | BASF Aktiengesellschaft (DE) | 1990-02-14 | — | — | EP | claimed |
| US-4777185-A | Phenyl phenoxyphenyl propenyl cyclopropane pesticides | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1988-10-11 | — | — | US | claimed |
| EP-0179788-A1 | PESTICIDES. | NAT RES DEV (GB) | 1986-05-07 | — | — | EP | claimed |
| WO-1985004651-A1 | IMPROVEMENTS RELATING TO PESTICIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-10-24 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023740-A1 | SODIUM CHANNEL INHIBITORS | TRPV1, SCN1A, SCN2A | HTR3A 1665/4885DRD2 3103/4885SLC2A1 500/4885 |
| US-20160304519-A1 | SERINE/THREONINE KINASE INHIBITORS | TTBK1, MAP3K1, TNNI3K | HTR3A 3957/4885DRD2 4873/4885SLC2A1 1147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.