Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 4/20 | 0.52 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30740941 | 1.00 | COMT (0.52) | COMTFTOCYP1A2HSP90AA1HSP90AB1 | |
| SCHEMBL30740906 | 0.89 | FTO (0.62) | COMTFTOCA12CA1CA2 | |
| SCHEMBL31520157 | 0.89 | FTO (0.62) | COMTFTOCA12CA1CA2 | |
| SCHEMBL30740902 | 0.84 | COMT (0.54) | COMTFTOCYP1A2HSP90AA1HSP90AB1 | |
| SCHEMBL32669761 | 0.81 | FTO (0.77) | COMTFTOALDH1A1EGFRKMT2A | |
| SCHEMBL30740960 | 0.76 | FTO (0.67) | COMTFTOHSP90AA1HSP90AB1CA12 | |
| SCHEMBL4608763 | 0.75 | FTO (0.68) | COMTFTOPKMALDH1A1KMT2A | |
| SCHEMBL4608767 | 0.75 | FTO (0.68) | COMTFTOPKMALDH1A1KMT2A | |
| SCHEMBL4609816 | 0.75 | FTO (0.68) | COMTFTOPKMALDH1A1KMT2A | |
| SCHEMBL23865165 | 0.74 | COMT (0.58) | COMTFTOCYP1A2HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119546566-A | FTO inhibitors | 瑞璞鑫(苏州)生物科技有限公司 | 2025-02-28 | — | — | CN | disclosed |