Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 3/20 | 0.54 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.40 |
| ▸ | PTP4A2 | Q12974 | 2/20 | 0.40 |
| ▸ | PTP4A1 | Q93096 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31520161 | 0.84 | COMT (0.52) | COMTFTOEGFRCYP1A2HSP90AA1 | |
| SCHEMBL30740941 | 0.84 | COMT (0.52) | COMTFTOEGFRCYP1A2HSP90AA1 | |
| SCHEMBL32669761 | 0.82 | FTO (0.77) | COMTFTOEGFRMEN1KMT2A | |
| SCHEMBL32670137 | 0.80 | FTO (0.80) | COMTFTOMEN1KMT2A | |
| SCHEMBL4609816 | 0.76 | FTO (0.68) | COMTFTOMEN1KMT2AALDH1A1 | |
| SCHEMBL4608763 | 0.76 | FTO (0.68) | COMTFTOMEN1KMT2AALDH1A1 | |
| SCHEMBL4608767 | 0.76 | FTO (0.68) | COMTFTOMEN1KMT2AALDH1A1 | |
| SCHEMBL31520157 | 0.74 | FTO (0.62) | COMTFTOEGFRMEN1KMT2A | |
| SCHEMBL30740906 | 0.74 | FTO (0.62) | COMTFTOEGFRMEN1KMT2A | |
| SCHEMBL23865165 | 0.74 | COMT (0.58) | COMTFTOEGFRCYP1A2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260035341-A1 | FTO INHIBITORS | RPXDS CO LTD (CN) | 2026-02-05 | — | — | US | disclosed |
| EP-4561975-A1 | FTO INHIBITORS | RPXDS Co., Ltd (CN) | 2025-06-04 | — | — | EP | disclosed |
| CN-119546566-A | FTO inhibitors | 瑞璞鑫(苏州)生物科技有限公司 | 2025-02-28 | — | — | CN | disclosed |
| WO-2024022491-A1 | FTO INHIBITORS | RPXDS CO., LTD (CN) | 2024-02-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260035341-A1 | FTO INHIBITORS | FTO, LDLR, GPR119 | COMT 52/4885FTO 1/4885PTPN1 902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.