Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.57 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.57 |
| ▸ | TNF | P01375 | 2/20 | 0.55 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.54 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31520459 | 0.98 | NPC1 (0.65) | NPC1GAAHTTRAB9ATNIK | |
| SCHEMBL31505240 | 0.98 | NPC1 (0.65) | NPC1GAAHTTRAB9ATNIK | |
| SCHEMBL31520460 | 0.98 | NPC1 (0.65) | NPC1GAAHTTRAB9ATNIK | |
| SCHEMBL31520444 | 0.90 | NPC1 (0.61) | NPC1RAB9AL3MBTL1L3MBTL3MBTD1 | |
| SCHEMBL31520463 | 0.89 | RAB9A (0.62) | NPC1HTTRAB9AL3MBTL1L3MBTL3 | |
| SCHEMBL31520466 | 0.89 | TNF (0.58) | NPC1GAARAB9AL3MBTL1L3MBTL3 | |
| SCHEMBL31520445 | 0.88 | HIF1A (0.65) | L3MBTL1L3MBTL3MBTD1TNFCYP2C9 | |
| SCHEMBL31520465 | 0.87 | HIF1A (0.64) | NPC1HTTRAB9AL3MBTL1L3MBTL3 | |
| SCHEMBL31520469 | 0.85 | RAB9A (0.53) | NPC1GAAHTTRAB9AL3MBTL1 | |
| SCHEMBL31520449 | 0.84 | TNF (0.58) | L3MBTL1L3MBTL3MBTD1TNFNOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823027-A | Piperidinyl piperidine modified beta-carboline open ring compound, and preparation method and application thereof | 南通大学 | 2025-04-15 | — | — | CN | claimed |
| CN-119823027-A | Piperidinyl piperidine modified beta-carboline open ring compound, and preparation method and application thereof | 南通大学 | 2025-04-15 | — | — | CN | disclosed |