Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.65 |
| ▸ | EPAS1 | Q99814 | 6/20 | 0.65 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.55 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.55 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TNF | P01375 | 1/20 | 0.53 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.53 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.53 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.53 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.53 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.53 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.53 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.53 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.53 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.52 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31520463 | 0.90 | RAB9A (0.62) | HIF1AEPAS1MBTD1L3MBTL3L3MBTL1 | |
| SCHEMBL31520444 | 0.89 | NPC1 (0.61) | MBTD1L3MBTL3L3MBTL1TNFACKR3 | |
| SCHEMBL31520449 | 0.88 | TNF (0.58) | HIF1AEPAS1MBTD1L3MBTL3L3MBTL1 | |
| SCHEMBL31520466 | 0.88 | TNF (0.58) | MBTD1L3MBTL3L3MBTL1TNFACKR3 | |
| SCHEMBL31520448 | 0.88 | NPC1 (0.62) | MBTD1L3MBTL3L3MBTL1TNFCYP2C9 | |
| SCHEMBL31505240 | 0.85 | NPC1 (0.65) | MBTD1L3MBTL3L3MBTL1TNFCYP2C9 | |
| SCHEMBL31520459 | 0.85 | NPC1 (0.65) | MBTD1L3MBTL3L3MBTL1TNFCYP2C9 | |
| SCHEMBL31520460 | 0.85 | NPC1 (0.65) | MBTD1L3MBTL3L3MBTL1TNFCYP2C9 | |
| SCHEMBL31520465 | 0.85 | HIF1A (0.64) | HIF1AEPAS1MBTD1L3MBTL3L3MBTL1 | |
| SCHEMBL31520447 | 0.84 | MBTD1 (0.53) | HIF1AEPAS1MBTD1L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823027-A | Piperidinyl piperidine modified beta-carboline open ring compound, and preparation method and application thereof | 南通大学 | 2025-04-15 | — | — | CN | claimed |
| CN-119823027-A | Piperidinyl piperidine modified beta-carboline open ring compound, and preparation method and application thereof | 南通大学 | 2025-04-15 | — | — | CN | disclosed |