Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18128520 | 0.88 | ALDH1A1 (0.31) | KHKALDH1A1ENPP1L3MBTL1 | |
| SCHEMBL29654262 | 0.88 | ALDH1A1 (0.31) | KHKALDH1A1ENPP1L3MBTL1 | |
| SCHEMBL25805404 | 0.78 | L3MBTL1 (0.34) | ALDH1A1KDM1AENPP1L3MBTL1 | |
| SCHEMBL23986037 | 0.77 | ALDH1A1 (0.38) | KHKALDH1A1L3MBTL1 | |
| SCHEMBL24425031 | 0.77 | — | — | |
| SCHEMBL24579947 | 0.75 | KHK (0.34) | KHKKDM1AL3MBTL1 | |
| SCHEMBL18153433 | 0.74 | MAPK14 (0.37) | KHKALDH1A1ADORA2AADORA1 | |
| SCHEMBL24424957 | 0.74 | MEN1 (0.31) | ALDH1A1 | |
| SCHEMBL30260039 | 0.74 | MEN1 (0.31) | ALDH1A1 | |
| SCHEMBL26310755 | 0.74 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119790059-A | Heterocyclic compounds as KRAS inhibitors, their preparation and therapeutic use | 上海科州药物股份有限公司 | 2025-04-08 | — | — | CN | disclosed |