Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 11/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2504578 | 0.73 | OPRL1 (0.45) | OPRL1OPRM1OPRD1OPRK1ADRB2 | |
| SCHEMBL31521476 | 0.73 | OPRL1 (0.45) | OPRL1OPRM1OPRD1OPRK1ADRB2 | |
| SCHEMBL29609179 | 0.70 | ADRB2 (0.46) | OPRL1OPRM1OPRD1OPRK1ADRB2 | |
| SCHEMBL29609167 | 0.70 | ADRB2 (0.46) | OPRL1OPRM1OPRD1OPRK1ADRB2 | |
| SCHEMBL1351279 | 0.70 | MAOA (0.41) | ADRB2AOC3NFKB1HIF1ABLM | |
| SCHEMBL31521264 | 0.70 | ADRB2 (0.46) | OPRL1OPRM1OPRD1OPRK1ADRB2 | |
| SCHEMBL9940818 | 0.69 | ADRB2 (0.45) | OPRL1ADRB2ADRB1AOC3CYP2D6 | |
| SCHEMBL17684399 | 0.69 | SLC6A2 (0.41) | OPRL1OPRM1OPRD1OPRK1ADRB2 | |
| SCHEMBL11606505 | 0.69 | TSHR (0.50) | OPRL1ADRB2ADRB1AOC3CYP2D6 | |
| SCHEMBL17684317 | 0.67 | SLC6A4 (0.40) | OPRL1OPRM1OPRD1OPRK1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096957-A1 | RAS-PI3K INHIBITORS AND USES THEREOF | VIVIDION THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |