Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 1.00 |
| ▸ | CXCR1 | P25024 | 5/20 | 0.70 |
| ▸ | CXCR2 | P25025 | 5/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.70 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.70 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.70 |
| ▸ | ALB | P02768 | 1/20 | 0.70 |
| ▸ | ESR1 | P03372 | 1/20 | 0.70 |
| ▸ | RARB | P10826 | 1/20 | 0.70 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | HTR2A | P28223 | 1/20 | 0.70 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.70 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.70 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL260688 | 1.00 | EPHX1 (1.00) | EPHX1CXCR1CXCR2PTGS1PTGS2 | |
| SCHEMBL1883571 | 1.00 | EPHX1 (1.00) | EPHX1CXCR1CXCR2PTGS1PTGS2 | |
| Hydrochloric Acid SCHEMBL3424822 | 0.98 | EPHX1 (0.96) | EPHX1CXCR1CXCR2PTGS1PTGS2 | |
| SCHEMBL1082216 | 0.90 | EPHX1 (0.81) | EPHX1CXCR1CXCR2PTGS1PTGS2 | |
| SCHEMBL11641216 | 0.85 | EPHX1 (0.74) | EPHX1CXCR1CXCR2PTGS1PTGS2 | |
| SCHEMBL13802425 | 0.84 | EPHX1 (0.72) | EPHX1CXCR1CXCR2PTGS1PTGS2 | |
| SCHEMBL4471196 | 0.82 | CXCR1 (0.79) | EPHX1CXCR1CXCR2PTGS1PTGS2 | |
| Ibuprofen SCHEMBL239446 | 0.82 | PTGS1 (1.00) | EPHX1CXCR1CXCR2PTGS1PTGS2 | |
| SCHEMBL1526008 | 0.82 | EPHX1 (0.70) | EPHX1CXCR1CXCR2PTGS1PTGS2 | |
| SCHEMBL22509339 | 0.82 | EPHX1 (0.70) | EPHX1CXCR1CXCR2PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043152-A1 | METHODS OF DEALKENYLATIVE AMINATION AND AZIDATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-02-27 | — | — | WO | disclosed |
| CN-117105822-A | Synthesis method of (R) -3- (tertiary Ding Yangtan group) amino-2-methylpropanoic acid | 杭州澳赛诺生物科技有限公司 | 2023-11-24 | — | — | CN | disclosed |
| EP-4272761-A2 | COMPOSITIONS FOR TREATING OPHTHALMIC CONDITIONS | Medicon Pharmaceuticals, Inc. (US) | 2023-11-08 | — | — | EP | disclosed |
| EP-2990410-A1 | CHEMICALLY MODIFIED OLIGONUCLEOTIDES | Alnylam Pharmaceuticals Inc. (US) | 2016-03-02 | — | — | EP | disclosed |
| US-7705050-B2 | Amides, useful in the inhibition of IL-8-induced chemotaxis of neutrophils | DOMPÉ FARMACEUTICI S.P.A. (IT) | 2010-04-27 | — | — | US | disclosed |
| EP-1255726-B1 | (R)-2-ARYL-PROPIONAMIDES, USEFUL IN THE INHIBITION OF IL-8 INDUCED CHEMIOTAXIS OF NEUTROPHILS | DOMPE PHA R MA SPA RES & MFG (IT) | 2009-11-11 | — | — | EP | disclosed |
| CN-100513386-C | Amides for inhibiting interleukin 8-induced chemotaxis of neutrophils | DOMP S P A (IT) | 2009-07-15 | — | — | CN | disclosed |
| CN-1479715-A | Amides for inhibiting interleukin 8-induced chemotaxis of neutrophils | ��ķ�ɷ�����˾ | 2004-03-03 | — | — | CN | disclosed |
| EP-1255726-A2 | (R)-2-ARYL-PROPIONAMIDES, USEFUL IN THE INHIBITION OF IL-8 INDUCED CHEMIOTAXIS OF NEUTROPHILS | Dompé S.P.A. (IT) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001058852-A2 | (R)-2-ARYL-PROPIONAMIDES, USEFUL IN THE INHIBITION OF IL-8-INDUCED CHEMIOTAXIS OF NEUTROPHILS | Dompé S.p.A. (IT) | 2001-08-16 | — | — | WO | disclosed |
| US-5191095-A | Preparation of ibuprofen | ETHYL CORPORATION (US) | 1993-03-02 | — | — | US | disclosed |