Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.59 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.59 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.59 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.59 |
| ▸ | ALB | P02768 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | RARB | P10826 | 1/20 | 0.59 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.59 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30686891 | 0.87 | PTGS2 (0.76) | EPHX1PTGS1PTGS2CXCR1CXCR2 | |
| SCHEMBL260688 | 0.84 | EPHX1 (1.00) | EPHX1PTGS1PTGS2CXCR1CXCR2 | |
| SCHEMBL3152241 | 0.84 | EPHX1 (1.00) | EPHX1PTGS1PTGS2CXCR1CXCR2 | |
| SCHEMBL1883571 | 0.84 | EPHX1 (1.00) | EPHX1PTGS1PTGS2CXCR1CXCR2 | |
| SCHEMBL11237591 | 0.83 | TBXAS1 (0.59) | PTGS1PTGS2CXCR1CXCR2AKR1C3 | |
| Hydrochloric Acid SCHEMBL3424822 | 0.82 | EPHX1 (0.96) | EPHX1PTGS1PTGS2CXCR1CXCR2 | |
| SCHEMBL27473580 | 0.82 | PTGS1 (0.56) | EPHX1PTGS1PTGS2CXCR1CXCR2 | |
| SCHEMBL9311732 | 0.82 | PTGS1 (0.56) | EPHX1PTGS1PTGS2CXCR1CXCR2 | |
| SCHEMBL27480611 | 0.82 | PTGS1 (0.56) | EPHX1PTGS1PTGS2CXCR1CXCR2 | |
| SCHEMBL23582689 | 0.79 | CA2 (0.52) | EPHX1PTGS1PTGS2CXCR1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844001-B1 | METABOLITES OF 2-ARYLPROPIONIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE PHA R MA SPA RES & MFG (IT) | 2009-06-10 | — | — | EP | disclosed |
| US-20090131441-A1 | Metabolites Of 2-Arylpropionic Acid Derivatives And Pharmaceutical Compositions Containing Them | DOMPE PHAR.R.MA S.P.A. (IT) | 2009-05-21 | — | — | US | disclosed |
| US-20090131441-A1 | Metabolites Of 2-Arylpropionic Acid Derivatives And Pharmaceutical Compositions Containing Them | DOMPE PHAR.R.MA S.P.A. (IT) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131441-A1 | Metabolites Of 2-Arylpropionic Acid Derivatives And Pharmaceutical Compositions Containing Them | CXCR2, CXCR3, MMP8 | EPHX1 831/4885PTGS1 72/4885PTGS2 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.