SCHEMBL31522590

SCHEMBL31522590

CC(C)(NC(=O)OC1CN2CCC1CC2)c1ccc(F)c(-c2cccnc2)c1

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ NTMT1 Q9BV86 20/20 0.63
▸ UGCG Q16739 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31522586 0.91 NTMT1 (0.54) NTMT1UGCG
SCHEMBL31522593 0.90 NTMT1 (0.57) NTMT1UGCG
SCHEMBL31522589 0.90 NTMT1 (0.58) NTMT1UGCG
SCHEMBL31522582 0.86 NTMT1 (0.61) NTMT1UGCG
SCHEMBL31522596 0.83 NTMT1 (0.60) NTMT1UGCG
SCHEMBL31522591 0.80 NTMT1 (0.55) NTMT1UGCG
SCHEMBL29415411 0.79 NTMT1 (0.61) NTMT1UGCG
SCHEMBL12614770 0.78 NTMT1 (0.58) NTMT1UGCG
SCHEMBL19844440 0.78 NTMT1 (0.61) NTMT1UGCG
SCHEMBL12696495 0.78 NTMT1 (0.61) NTMT1UGCG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4559918-A2 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS Genzyme Corporation (US) 2025-05-28 — — EP disclosed
EP-3673906-B1 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS GENZYME CORP (US) 2025-05-14 — — EP disclosed
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