Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.30 |
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31523285 | 0.98 | ALOX5AP (0.38) | ALOX5APFEN1CA2CA1CA9 | |
| Hydrochloric Acid SCHEMBL25343166 | 0.79 | JAK2 (0.36) | CA2CA1CA9MEP1BHTR2A | |
| SCHEMBL21468519 | 0.76 | KMT2A (0.39) | MEP1B | |
| SCHEMBL1675886 | 0.75 | ALOX5AP (0.49) | ALOX5APFEN1CA2CA4NQO2 | |
| SCHEMBL29509682 | 0.74 | MEP1B (0.44) | ALOX5APFEN1CA2CA1CA4 | |
| SCHEMBL4024514 | 0.74 | MEP1B (0.44) | ALOX5APFEN1CA2CA1CA4 | |
| Hydrochloric Acid SCHEMBL28339215 | 0.74 | KDM1A (0.38) | CA2CA1CA9KDM1AKCNH2 | |
| SCHEMBL15561571 | 0.73 | EGFR (0.43) | CA2CA1CA9CA4NQO2 | |
| SCHEMBL31523571 | 0.73 | CA2 (0.34) | CA2CA4 | |
| SCHEMBL4574409 | 0.72 | TUBB1 (0.41) | ALOX5APFEN1CA2CA4NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346600-A1 | TRICYCLIC DERIVATIVES AND RELATED USES | MOMA THERAPEUTICS, INC. | 2025-11-13 | — | — | US | disclosed |
| WO-2025054488-A1 | TRICYCLIC DERIVATIVES AND RELATED USES | MOMA THERAPEUTICS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250346600-A1 | TRICYCLIC DERIVATIVES AND RELATED USES | WRN, RECQL, BLM | ALOX5AP 3375/4885FEN1 27/4885CA2 4248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.