Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 4/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.33 |
| ▸ | PRMT3 | O60678 | 2/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.33 |
| ▸ | PRMT9 | Q6P2P2 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 2/20 | 0.31 |
| ▸ | NNMT | P40261 | 1/20 | 0.30 |
| ▸ | NADK | O95544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31526204 | 0.92 | PRMT5 (0.35) | DOT1LPRMT5PRMT3DNMT1PRMT9 | |
| SCHEMBL31526151 | 0.89 | PRMT5 (0.35) | DOT1LPRMT5PRMT3DNMT1EHMT2 | |
| SCHEMBL31526233 | 0.89 | DOT1L (0.43) | DOT1LPRMT5PRMT3DNMT1EHMT2 | |
| SCHEMBL31526088 | 0.87 | ADK (0.36) | DOT1LPRMT5PRMT3DNMT1EHMT2 | |
| SCHEMBL31526183 | 0.86 | DOT1L (0.46) | DOT1LPRMT5PRMT3DNMT1EHMT2 | |
| SCHEMBL31526181 | 0.86 | ADK (0.41) | DOT1LPRMT5PRMT3DNMT1PRMT9 | |
| SCHEMBL31526240 | 0.86 | ADK (0.39) | DOT1LPRMT5PRMT3DNMT1EHMT2 | |
| SCHEMBL31526254 | 0.86 | PRMT5 (0.41) | PRMT5PRMT9ADK | |
| SCHEMBL31526128 | 0.85 | ADK (0.33) | DOT1LPRMT5PRMT3DNMT1EHMT2 | |
| SCHEMBL31526221 | 0.85 | PRMT5 (0.34) | DOT1LPRMT5PRMT3DNMT1EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025098545-A1 | NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ) | 2025-05-15 | — | — | WO | disclosed |
| EP-4553080-A1 | NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES | Ustav Organicke Chemie a Biochemie AV CR, v.v.i. (CZ) | 2025-05-14 | — | — | EP | disclosed |