SCHEMBL31526239

SCHEMBL31526239

Cc1noc(-c2ccccc2)c1CSC[C@H]1O[C@@H](n2cc(C3CCCCC3)c3c(N)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ METTL3 Q86U44 9/20 0.52
▸ PRMT5 O14744 10/20 0.48
▸ WDR77 Q9BQA1 1/20 0.44
▸ ADK P55263 3/20 0.43
▸ DOT1L Q8TEK3 4/20 0.43
▸ PRMT3 O60678 2/20 0.43
▸ DNMT1 P26358 2/20 0.43
▸ NNMT P40261 1/20 0.43
▸ PRMT9 Q6P2P2 1/20 0.42
▸ EHMT2 Q96KQ7 1/20 0.41
▸ NADK O95544 1/20 0.41
▸ GNMT Q14749 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31526319 0.99 METTL3 (0.51) METTL3PRMT5WDR77ADKDOT1L
SCHEMBL31526370 0.89 PRMT5 (0.52) METTL3PRMT5ADKDOT1LPRMT3
SCHEMBL31526186 0.88 ADK (0.58) PRMT5ADKDOT1LPRMT3DNMT1
SCHEMBL31570691 0.87 ADK (0.41) METTL3PRMT5ADKDOT1LPRMT3
SCHEMBL31526255 0.87 ADK (0.56) PRMT5ADKDOT1LPRMT3DNMT1
SCHEMBL31570710 0.87 ADK (0.47) PRMT5WDR77ADKDOT1LPRMT3
SCHEMBL31526383 0.86 DOT1L (0.47) PRMT5ADKDOT1LPRMT3DNMT1
SCHEMBL31526392 0.86 ADK (0.49) PRMT5ADKDOT1LPRMT3DNMT1
SCHEMBL31526190 0.86 ADK (0.45) PRMT5ADKDOT1LPRMT3DNMT1
SCHEMBL31526342 0.85 ADK (0.55) PRMT5ADKDOT1LPRMT3DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025098545-A1 NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ) 2025-05-15 — — WO disclosed
EP-4553080-A1 NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES Ustav Organicke Chemie a Biochemie AV CR, v.v.i. (CZ) 2025-05-14 — — EP disclosed
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