Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 5/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.41 |
| ▸ | PRMT3 | O60678 | 2/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | RNMT | O43148 | 1/20 | 0.38 |
| ▸ | NAE1 | Q13564 | 3/20 | 0.38 |
| ▸ | UBA3 | Q8TBC4 | 2/20 | 0.38 |
| ▸ | UBA1 | P22314 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
| ▸ | PRMT9 | Q6P2P2 | 1/20 | 0.38 |
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31570702 | 0.91 | DOT1L (0.43) | DOT1LPRMT5PRMT3DNMT1EHMT2 | |
| SCHEMBL31526091 | 0.90 | DOT1L (0.45) | DOT1LPRMT5PRMT3DNMT1EHMT2 | |
| SCHEMBL31526284 | 0.89 | DOT1L (0.46) | DOT1LPRMT5PRMT3DNMT1EHMT2 | |
| SCHEMBL31526146 | 0.88 | RIPK2 (0.33) | CA2RNMTNAE1UBA3UBA1 | |
| SCHEMBL31526092 | 0.85 | ADK (0.43) | DOT1LPRMT5PRMT3DNMT1EHMT2 | |
| SCHEMBL31526324 | 0.84 | DOT1L (0.47) | DOT1LPRMT5PRMT3DNMT1EHMT2 | |
| SCHEMBL31526205 | 0.83 | RNMT (0.48) | DOT1LPRMT5PRMT3DNMT1EHMT2 | |
| SCHEMBL31526327 | 0.83 | DOT1L (0.45) | DOT1LPRMT5PRMT3DNMT1EHMT2 | |
| SCHEMBL31526120 | 0.82 | DNMT1 (0.49) | PRMT5DNMT1ADK | |
| SCHEMBL31526346 | 0.81 | DOT1L (0.45) | DOT1LPRMT5PRMT3DNMT1EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025098545-A1 | NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ) | 2025-05-15 | — | — | WO | disclosed |
| EP-4553080-A1 | NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES | Ustav Organicke Chemie a Biochemie AV CR, v.v.i. (CZ) | 2025-05-14 | — | — | EP | disclosed |