Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PPIA | P62937 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816556 | 0.98 | NPSR1 (0.41) | NPSR1PPIAOPRL1OPRD1OPRM1 | |
| SCHEMBL16757411 | 0.94 | NPSR1 (0.42) | NPSR1PPIAOPRL1OPRD1OPRM1 | |
| SCHEMBL6816871 | 0.92 | NPSR1 (0.44) | NPSR1PPIAOPRL1OPRD1OPRM1 | |
| SCHEMBL31531562 | 0.90 | OPRL1 (0.39) | NPSR1PPIAOPRL1OPRD1OPRM1 | |
| SCHEMBL30590793 | 0.89 | ALDH1A1 (0.43) | ALDH1A1GAACYP2C19HTTLMNA | |
| SCHEMBL232028 | 0.88 | NPSR1 (0.39) | NPSR1PPIAOPRL1OPRD1OPRM1 | |
| SCHEMBL2707689 | 0.81 | HCN4 (0.40) | NPSR1OPRL1OPRD1OPRM1ALDH1A1 | |
| SCHEMBL25435107 | 0.80 | NPSR1 (0.33) | NPSR1PPIAOPRL1OPRD1OPRM1 | |
| SCHEMBL6508506 | 0.80 | CYP1A2 (0.37) | NPSR1OPRL1OPRD1OPRM1ALDH1A1 | |
| SCHEMBL18588661 | 0.78 | USP2 (0.36) | NPSR1PPIAUSP2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076523-A1 | RAS INHIBITORS AND METHODS OF USE THEREOF | KESTREL THERAPEUTICS, INC. (US) | 2025-04-10 | — | — | WO | disclosed |