SCHEMBL31528064

SCHEMBL31528064

CCN1C(=O)Cc2c(Br)c(C)cc(F)c21

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HSP90B1 P14625 2/20 0.34
TRAP1 Q12931 2/20 0.34
HSP90AA1 P07900 1/20 0.34
GSK3B P49841 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31528072 0.86 GSK3B (0.36) GSK3BSMN1; SMN2
SCHEMBL31528155 0.82 GSK3B (0.34) HSP90B1TRAP1HSP90AA1GSK3BSMN1; SMN2
SCHEMBL31528058 0.76 HSP90B1 (0.35) HSP90B1TRAP1HSP90AA1GSK3B
SCHEMBL31528250 0.75 ALDH1A1 (0.31)
SCHEMBL31528175 0.73 GSK3B (0.41) HSP90B1TRAP1HSP90AA1GSK3BSMN1; SMN2
SCHEMBL31528055 0.72 ALDH1A1 (0.35)
SCHEMBL31528083 0.71 GSK3B (0.41) GSK3BSMN1; SMN2
SCHEMBL19630004 0.70 BRD4 (0.35) HSP90B1TRAP1GSK3B
SCHEMBL31528036 0.70 GSK3B (0.40) GSK3BSMN1; SMN2
SCHEMBL31528031 0.70 TRAP1 (0.36) HSP90B1TRAP1HSP90AA1GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025078811-A1 CANNABINOID COMPOUNDS AND USES THEREOF JAZZ PHARMACEUTICALS RESEARCH UK LIMITED (GB) 2025-04-17 WO claimed
WO-2025078811-A1 CANNABINOID COMPOUNDS AND USES THEREOF JAZZ PHARMACEUTICALS RESEARCH UK LIMITED (GB) 2025-04-17 WO disclosed