Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6223730 | 0.85 | POLB (0.47) | SIGMAR1DRD1DRD4DRD5 | |
| SCHEMBL23926362 | 0.84 | HRH3 (0.55) | HRH3SLC6A3SIGMAR1KCNH2HTR2A | |
| SCHEMBL23094139 | 0.83 | HRH3 (0.57) | HRH3SLC6A3SIGMAR1KCNH2HTR2A | |
| SCHEMBL5909670 | 0.82 | ALDH1A1 (0.53) | HRH3 | |
| SCHEMBL22322105 | 0.81 | ALDH1A1 (0.56) | HRH3 | |
| SCHEMBL13038416 | 0.79 | HRH3 (0.46) | HRH3SLC6A3SIGMAR1KCNH2LTA4H | |
| SCHEMBL1892119 | 0.73 | MEN1 (0.63) | LTA4HDRD3DRD1DRD4DRD5 | |
| SCHEMBL4932037 | 0.73 | SIGMAR1 (0.67) | HRH3SLC6A3SIGMAR1KCNH2HTR2A | |
| SCHEMBL9254022 | 0.73 | HRH3 (0.62) | HRH3SLC6A3SIGMAR1KCNH2 | |
| SCHEMBL6377779 | 0.73 | HRH3 (0.62) | HRH3SLC6A3SIGMAR1KCNH2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113454086-B | Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR7 agonists | 百济神州有限公司 | 2025-03-14 | — | — | CN | disclosed |