Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21936057 | 0.88 | MAPT (0.46) | RAB9ANPC1MAPK1SMN1; SMN2ELANE | |
| SCHEMBL21936036 | 0.87 | PTGS1 (0.44) | RAB9ANPC1MAPK1SMN1; SMN2ELANE | |
| SCHEMBL20876119 | 0.86 | PTGS1 (0.44) | RAB9ANPC1MAPK1SMN1; SMN2ELANE | |
| SCHEMBL31528527 | 0.85 | RAB9A (0.50) | RAB9ANPC1MAPK1SMN1; SMN2CYP1A2 | |
| SCHEMBL31164721 | 0.84 | RAB9A (0.52) | RAB9ANPC1MAPK1SMN1; SMN2CYP1A2 | |
| SCHEMBL21937178 | 0.84 | PTGS1 (0.42) | RAB9ANPC1MAPK1SMN1; SMN2ELANE | |
| SCHEMBL31528577 | 0.84 | RAB9A (0.49) | RAB9ANPC1MAPK1SMN1; SMN2CYP1A2 | |
| SCHEMBL20876131 | 0.83 | PTGS1 (0.41) | RAB9ANPC1MAPK1SMN1; SMN2ELANE | |
| SCHEMBL20876163 | 0.83 | PTGS1 (0.41) | RAB9ANPC1MAPK1SMN1; SMN2ELANE | |
| SCHEMBL1445392 | 0.77 | NPC1 (0.56) | RAB9ANPC1MAPK1SMN1; SMN2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025077671-A1 | POLYSUBSTITUTED ARYL DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2025-04-17 | — | — | WO | disclosed |