Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ADK | P55263 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31529133 | 0.86 | PAX8 (0.49) | PAX8IRAK4 | |
| SCHEMBL31529245 | 0.85 | PAX8 (0.41) | PAX8SMN1; SMN2 | |
| SCHEMBL31529311 | 0.84 | PAX8 (0.72) | PAX8BRAFSMN1; SMN2 | |
| SCHEMBL31529204 | 0.82 | PAX8 (0.44) | PAX8IRAK4 | |
| SCHEMBL31529222 | 0.79 | IRAK4 (0.41) | PAX8IRAK4ADORA1 | |
| SCHEMBL31529092 | 0.79 | IRAK4 (0.41) | PAX8IRAK4ADORA1 | |
| SCHEMBL31529150 | 0.79 | IRAK4 (0.41) | PAX8IRAK4ADORA1 | |
| SCHEMBL31529185 | 0.78 | PAX8 (0.46) | PAX8ADORA1SMN1; SMN2ADK | |
| SCHEMBL31529191 | 0.78 | IRAK4 (0.47) | PAX8IRAK4BRAFTNNI3KADK | |
| SCHEMBL31529146 | 0.75 | PAX8 (0.42) | PAX8ADORA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090774-A1 | CHEMOTHERAPEUTIC COMPOUNDS AND METHODS OF USE | SEAGEN INC. (US) | 2025-05-01 | — | — | WO | disclosed |