Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | JAK3 | P52333 | 13/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TEC | P42680 | 1/20 | 0.38 |
| ▸ | TXK | P42681 | 1/20 | 0.38 |
| ▸ | BLK | P51451 | 1/20 | 0.38 |
| ▸ | BMX | P51813 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | ITK | Q08881 | 1/20 | 0.38 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31529181 | 0.86 | PAX8 (0.53) | PAX8IRAK4 | |
| SCHEMBL31529185 | 0.85 | PAX8 (0.46) | PAX8 | |
| SCHEMBL31529129 | 0.82 | PAX8 (0.41) | PAX8JAK3RETIRAK4JAK1 | |
| SCHEMBL31529311 | 0.81 | PAX8 (0.72) | PAX8BTK | |
| SCHEMBL31529142 | 0.76 | PAX8 (0.47) | PAX8 | |
| SCHEMBL31529245 | 0.76 | PAX8 (0.41) | PAX8 | |
| SCHEMBL31529146 | 0.76 | PAX8 (0.42) | PAX8 | |
| SCHEMBL31529138 | 0.72 | PAX8 (0.53) | PAX8 | |
| SCHEMBL31529122 | 0.72 | IRAK4 (0.42) | JAK3IRAK4JAK1TECTXK | |
| SCHEMBL31529348 | 0.70 | PAX8 (0.58) | PAX8BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090774-A1 | CHEMOTHERAPEUTIC COMPOUNDS AND METHODS OF USE | SEAGEN INC. (US) | 2025-05-01 | — | — | WO | disclosed |