Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31529255 | 1.00 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL31529078 | 0.85 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL31529201 | 0.82 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2CYP2C19ADORA2A | |
| SCHEMBL17578532 | 0.68 | PTPN1 (0.39) | — | |
| SCHEMBL19793413 | 0.68 | PTPN1 (0.39) | — | |
| SCHEMBL18040445 | 0.67 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL30679403 | 0.66 | YTHDC1 (0.69) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL20322942 | 0.66 | YTHDC1 (0.69) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL218275 | 0.65 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL29366631 | 0.65 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090774-A1 | CHEMOTHERAPEUTIC COMPOUNDS AND METHODS OF USE | SEAGEN INC. (US) | 2025-05-01 | — | — | WO | disclosed |