Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31529256 | 0.82 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2CYP2C19ADORA2A | |
| SCHEMBL31529255 | 0.82 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2CYP2C19ADORA2A | |
| SCHEMBL31529155 | 0.72 | ADORA1 (0.43) | NPC1RAB9ASMN1; SMN2ADORA2AADORA1 | |
| SCHEMBL20322942 | 0.72 | YTHDC1 (0.69) | NPC1RAB9ASMN1; SMN2CYP2C19TP53 | |
| SCHEMBL30679403 | 0.72 | YTHDC1 (0.69) | NPC1RAB9ASMN1; SMN2CYP2C19TP53 | |
| SCHEMBL31529233 | 0.72 | ADORA1 (0.44) | NPC1RAB9ASMN1; SMN2CYP2C19ADORA2A | |
| SCHEMBL9885102 | 0.70 | NPC1 (0.71) | NPC1RAB9ASMN1; SMN2CYP2C19TP53 | |
| SCHEMBL17847679 | 0.69 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2CYP2C19TP53 | |
| SCHEMBL31529112 | 0.69 | KDM4E (0.30) | HSD17B10ALDH1A1 | |
| SCHEMBL30411218 | 0.68 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2CYP2C19TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090774-A1 | CHEMOTHERAPEUTIC COMPOUNDS AND METHODS OF USE | SEAGEN INC. (US) | 2025-05-01 | — | — | WO | disclosed |