Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | PBK | Q96KB5 | 3/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.32 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31529099 | 0.85 | PAX8 (0.56) | PAX8 | |
| SCHEMBL31529138 | 0.79 | PAX8 (0.53) | PAX8PBKCYP3A4 | |
| SCHEMBL31529092 | 0.76 | IRAK4 (0.41) | PAX8SPHK1 | |
| SCHEMBL31529222 | 0.76 | IRAK4 (0.41) | PAX8SPHK1 | |
| SCHEMBL31529312 | 0.75 | PAX8 (0.45) | PAX8CYP3A4 | |
| SCHEMBL31529290 | 0.75 | PAX8 (0.45) | PAX8CYP3A4 | |
| SCHEMBL31529302 | 0.74 | IRAK4 (0.41) | PAX8SPHK1CYP3A4 | |
| SCHEMBL31529281 | 0.74 | IRAK4 (0.41) | PAX8SPHK1CYP3A4 | |
| SCHEMBL31529218 | 0.74 | PAX8 (0.42) | PAX8 | |
| SCHEMBL31529295 | 0.73 | PAX8 (0.44) | PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090774-A1 | CHEMOTHERAPEUTIC COMPOUNDS AND METHODS OF USE | SEAGEN INC. (US) | 2025-05-01 | — | — | WO | disclosed |