Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 8/20 | 0.31 |
| ▸ | PAK4 | O96013 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31529302 | 1.00 | IRAK4 (0.41) | IRAK4PAX8ADORA1SPHK1PAK4 | |
| SCHEMBL31529163 | 0.86 | IRAK4 (0.41) | IRAK4PAX8ADORA1PAK4OPRM1 | |
| SCHEMBL31529092 | 0.84 | IRAK4 (0.41) | IRAK4PAX8ADORA1SPHK1 | |
| SCHEMBL31529222 | 0.84 | IRAK4 (0.41) | IRAK4PAX8ADORA1SPHK1 | |
| SCHEMBL31529206 | 0.82 | PAX8 (0.39) | PAX8 | |
| SCHEMBL31529099 | 0.80 | PAX8 (0.56) | PAX8 | |
| SCHEMBL31529218 | 0.79 | PAX8 (0.42) | PAX8 | |
| SCHEMBL31529294 | 0.79 | ADORA1 (0.41) | PAX8ADORA1CYP3A4 | |
| SCHEMBL31529310 | 0.77 | IRAK4 (0.36) | IRAK4PAX8ADORA1 | |
| SCHEMBL31529258 | 0.74 | PAX8 (0.41) | PAX8SPHK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090774-A1 | CHEMOTHERAPEUTIC COMPOUNDS AND METHODS OF USE | SEAGEN INC. (US) | 2025-05-01 | — | — | WO | disclosed |