Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ADK | P55263 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31529192 | 0.91 | PAX8 (0.55) | PAX8SMN1; SMN2HSD17B10TSHRTP53 | |
| SCHEMBL31529103 | 0.91 | PAX8 (0.51) | PAX8SMN1; SMN2HSD17B10TSHRTP53 | |
| SCHEMBL31529246 | 0.89 | PAX8 (0.53) | PAX8SMN1; SMN2HSD17B10TSHRTP53 | |
| SCHEMBL31529311 | 0.89 | PAX8 (0.72) | PAX8SMN1; SMN2HSD17B10TSHRTP53 | |
| SCHEMBL31529336 | 0.88 | PAX8 (0.60) | PAX8SMN1; SMN2HSD17B10TSHRTP53 | |
| SCHEMBL31529313 | 0.87 | PAX8 (0.68) | PAX8SMN1; SMN2HSD17B10TSHRTP53 | |
| SCHEMBL31529156 | 0.86 | PAX8 (0.56) | PAX8SMN1; SMN2HSD17B10TSHRTP53 | |
| SCHEMBL31529254 | 0.86 | PAX8 (0.69) | PAX8SMN1; SMN2HSD17B10TSHRTP53 | |
| SCHEMBL31529157 | 0.86 | PAX8 (0.69) | PAX8SMN1; SMN2HSD17B10TSHRTP53 | |
| SCHEMBL31529304 | 0.85 | PAX8 (0.57) | PAX8SMN1; SMN2ADKCYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090774-A1 | CHEMOTHERAPEUTIC COMPOUNDS AND METHODS OF USE | SEAGEN INC. (US) | 2025-05-01 | — | — | WO | disclosed |