Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HPD | P32754 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30662860 | 0.89 | KMT2A (0.54) | KMT2AHPDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL26604443 | 0.89 | KMT2A (0.54) | KMT2AHPDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL26401575 | 0.81 | ALDH1A1 (0.51) | KMT2AALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL26401595 | 0.80 | ALDH1A1 (0.50) | KMT2AHPDALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL30402800 | 0.80 | ALDH1A1 (0.50) | KMT2AHPDALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2521491 | 0.79 | HPGD (0.52) | KMT2AALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL28029191 | 0.79 | ALDH1A1 (0.49) | KMT2AALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL4870470 | 0.78 | HPD (0.64) | HPDSMN1; SMN2MAPTRAB9A | |
| SCHEMBL2991148 | 0.78 | HTT (0.53) | KMT2AHPDALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL2986814 | 0.77 | HPD (0.57) | KMT2AHPDALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025056073-A1 | INDAZOLONE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND USE | 中国科学院上海药物研究所 | 2025-03-20 | — | — | WO | disclosed |
| CN-119613374-A | Indazolone compound, preparation method thereof, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2025-03-14 | — | — | CN | disclosed |