Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25612072 | 1.00 | KDM4E (0.58) | KDM4EGLAAPEX1MYCNR4A1 | |
| Hydrochloric Acid SCHEMBL29919912 | 0.98 | KDM4E (0.56) | KDM4EGLAAPEX1MYCNR4A1 | |
| SCHEMBL4816871 | 0.85 | KDM4E (0.53) | KDM4EGLAAPEX1MYCNR4A1 | |
| SCHEMBL6844857 | 0.82 | KDM4E (0.55) | KDM4EGLAAPEX1MYCNR4A1 | |
| SCHEMBL3172005 | 0.82 | KDM4E (0.55) | KDM4EGLAAPEX1MYCNR4A1 | |
| SCHEMBL23243427 | 0.82 | KDM4E (0.55) | KDM4EGLAAPEX1MYCNR4A1 | |
| SCHEMBL31125276 | 0.82 | KDM4E (0.55) | KDM4EGLAAPEX1MYCNR4A1 | |
| SCHEMBL1400054 | 0.81 | KDM4E (0.53) | KDM4EGLAAPEX1MYCNR4A1 | |
| SCHEMBL31053264 | 0.81 | KDM4E (0.53) | KDM4EGLAAPEX1MYCNR4A1 | |
| SCHEMBL28047920 | 0.81 | KDM4E (0.53) | KDM4EGLAAPEX1MYCNR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120004861-A | Allosteric EGFR inhibitors and methods of use thereof | 达纳-法伯癌症研究所股份有限公司 | 2025-05-16 | — | — | CN | disclosed |