Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 4/20 | 0.69 |
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | CASP3 | P42574 | 2/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.56 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8358036 | 0.82 | POLB (0.72) | MAPK10TSHRMAPK1MAPTLMNA | |
| SCHEMBL8358322 | 0.80 | TSHR (0.71) | MAPK10TSHRMAPK1MAPTLMNA | |
| SCHEMBL5294918 | 0.78 | MAPK8 (0.68) | MAPK10MAPK1MAPTLMNAALDH1A1 | |
| SCHEMBL28722481 | 0.76 | MAPK8 (0.66) | MAPK10MAPK1MAPTLMNAALDH1A1 | |
| SCHEMBL16760967 | 0.76 | MAPK8 (0.66) | MAPK10MAPK1MAPTLMNAALDH1A1 | |
| SCHEMBL4749588 | 0.76 | SMN1; SMN2 (0.67) | MAPK10MAPK1MAPTLMNAALDH1A1 | |
| SCHEMBL7933290 | 0.76 | MAPK8 (0.66) | MAPK10MAPK1MAPTLMNAALDH1A1 | |
| SCHEMBL8354074 | 0.76 | MAPT (0.68) | MAPK10TSHRMAPK1MAPTLMNA | |
| SCHEMBL31538572 | 0.76 | POLB (0.56) | MAPTLMNAHSD17B10ALDH1A1TDP1 | |
| SCHEMBL22664821 | 0.76 | POLB (0.56) | MAPTLMNAHSD17B10ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025093590-A1 | HETEROARYL ESTER DERIVATIVES AS SODIUM CHANNEL INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2025-05-08 | — | — | WO | disclosed |