Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11725150 | 0.82 | TSHR (0.48) | CALM1IDO1TSHRALDH1A1LOXL2 | |
| SCHEMBL15302510 | 0.82 | CALM1 (0.45) | CALM1IDO1TSHRALDH1A1LOXL2 | |
| SCHEMBL3406066 | 0.78 | TP53 (0.43) | CALM1IDO1TSHRALDH1A1LOXL2 | |
| SCHEMBL15302419 | 0.78 | TP53 (0.43) | CALM1IDO1TSHRALDH1A1LOXL2 | |
| SCHEMBL11240991 | 0.75 | CALM1 (0.50) | CALM1IDO1TSHRALDH1A1LOXL2 | |
| SCHEMBL1728429 | 0.75 | CALM1 (0.50) | CALM1IDO1TSHRALDH1A1LOXL2 | |
| SCHEMBL15302971 | 0.74 | TP53 (0.46) | CALM1IDO1TSHRALDH1A1LOXL2 | |
| SCHEMBL15302085 | 0.72 | MAOB (0.37) | CALM1IDO1TSHRALDH1A1LOXL2 | |
| SCHEMBL15301904 | 0.72 | MAOB (0.37) | CALM1IDO1TSHRALDH1A1LOXL2 | |
| SCHEMBL15302538 | 0.72 | MAOB (0.37) | CALM1IDO1TSHRALDH1A1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE46657-E1 | Method of making a trihalosilane | DOW CORNING CORPORATION (US) | 2018-01-02 | — | — | US | disclosed |
| US-9163046-B2 | Process for producing substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-10-20 | — | — | US | disclosed |
| EP-2651954-B1 | METHOD OF MAKING A TRIHALOSILANE | DOW CORNING (US) | 2015-09-16 | — | — | EP | disclosed |
| EP-2780347-B1 | A METHOD FOR PREPARING A DIORGANODIHALOSILANE | DOW CORNING (US) | 2015-08-12 | — | — | EP | disclosed |
| US-8865927-B2 | Method for preparing a diorganodihalosilane | DOW CORNING CORPORATION (US) | 2014-10-21 | — | — | US | disclosed |
| EP-2780347-A1 | A METHOD FOR PREPARING A DIORGANODIHALOSILANE | Dow Corning Corporation (US) | 2014-09-24 | — | — | EP | disclosed |
| US-20140243494-A1 | Method for Preparing a Diorganodihalosilane | DOW SILICONES CORPORATION | 2014-08-28 | — | — | US | disclosed |
| US-8697022-B2 | Method of making a trihalosilane | DOW CORNING CORPORATION (US) | 2014-04-15 | — | — | US | disclosed |
| US-8674129-B2 | Method of making a diorganodihalosilane | DOW CORNING CORPORATION (US) | 2014-03-18 | — | — | US | disclosed |
| EP-2651954-A1 | METHOD OF MAKING A TRIHALOSILANE | Dow Corning Corporation (US) | 2013-10-23 | — | — | EP | disclosed |
| US-20130251617-A1 | Method of Making a Trihalosilane | DOW SILICONES CORPORATION | 2013-09-26 | — | — | US | disclosed |
| WO-2013074219-A1 | A METHOD FOR PREPARING A DIORGANODIHALOSILANE | DOW CORNING CORPORATION (US) | 2013-05-23 | — | — | WO | disclosed |
| WO-2012082385-A1 | METHOD OF MAKING A DIORGANODIHALOSILANE | DOW CORNING CORPORATION (US) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012082686-A1 | METHOD OF MAKING A TRIHALOSILANE | DOW CORNING CORPORATION (US) | 2012-06-21 | — | — | WO | disclosed |
| US-20100113717-A1 | Process For Producing Substituted Metallocene Compounds For Olefin Polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2010-05-06 | — | — | US | disclosed |
| US-7709670-B2 | Process for producing substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-05-04 | — | — | US | disclosed |
| EP-1866322-B1 | PROCESS FOR PRODUCING SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2010-02-24 | — | — | EP | disclosed |
| EP-1866322-A2 | PROCESS FOR PRODUCING SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | ExxonMobil Chemical Patents Inc. (US) | 2007-12-19 | — | — | EP | disclosed |
| US-20060160968-A1 | Process for producing substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-07-20 | — | — | US | disclosed |
| WO-2006065844-A2 | PROCESS FOR PRODUCING SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113717-A1 | Process For Producing Substituted Metallocene Compounds For Olefin Polymerization | OSBP, OSBPL3, OSBP2 | CALM1 4045/4885IDO1 2919/4885TSHR 4116/4885 |
| US-20060160968-A1 | Process for producing substituted metallocene compounds for olefin polymerization | OSBP, OSBPL3, OSBP2 | CALM1 4045/4885IDO1 2919/4885TSHR 4116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.