SCHEMBL31532299

SCHEMBL31532299

N[C@@H](CCn1oc(=O)[nH]c1=O)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 3/20 1.00
GRM2 Q14416 2/20 1.00
CYP1A2 P05177 5/20 0.71
KMT2A Q03164 3/20 0.71
MEN1 O00255 2/20 0.71
CYP2C19 P33261 2/20 0.71
KDM4E B2RXH2 2/20 0.71
BLM P54132 2/20 0.71
GRM1 Q13255 2/20 0.71
GRM3 Q14832 2/20 0.71
ALDH1A1 P00352 1/20 0.71
CYP3A4 P08684 1/20 0.71
NFKB1 P19838 1/20 0.71
MAPK1 P28482 1/20 0.71
FOLH1 Q04609 1/20 0.71
HIF1A Q16665 1/20 0.71
TDP1 Q9NUW8 1/20 0.71
SLC7A11 Q9UPY5 1/20 0.71
GRIA1 P42261 10/20 0.37
GRIA2 P42262 10/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quisqualate SCHEMBL3674132 0.83 CYP1A2 (1.00) GRM5GRM2CYP1A2KMT2AMEN1
Quisqualate SCHEMBL136819 0.83 CYP1A2 (1.00) GRM5GRM2CYP1A2KMT2AMEN1
Quisqualate SCHEMBL27790631 0.82 CYP1A2 (0.97) GRM5GRM2CYP1A2KMT2AMEN1
SCHEMBL31532300 0.71 GRM5 (0.55) GRM5GRM2CYP1A2KMT2AMEN1
SCHEMBL12648453 0.71 GRM5 (0.54) GRM5GRM2CYP1A2KMT2AMEN1
SCHEMBL24115254 0.71 GRM5 (0.55) GRM5GRM2CYP1A2KMT2AMEN1
SCHEMBL13319913 0.70 GRM2 (0.54) GRM5GRM2CYP1A2KMT2AMEN1
Bromide SCHEMBL9206069 0.70 GRM5 (0.53) GRM5GRM2CYP1A2KMT2AMEN1
SCHEMBL24115242 0.69 GRM5 (0.52) GRM5GRM2CYP1A2KMT2AMEN1
SCHEMBL1688782 0.67 GRM5 (0.50) GRM5GRM2CYP1A2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119954773-A PSMA compounds, pharmaceutical compositions comprising the same and uses thereof 苏州威智创科生物有限公司 2025-05-09 CN disclosed
WO-2025092841-A1 PSMA COMPOUND, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AND USE THEREOF 山东威智知科药业有限公司 2025-05-08 WO disclosed